:root{--bg: #FFFFFF;--surface: #F1F5F9;--border: #E2E8F0;--accent: #10B981;--accent-hover: #059669;--text: #0F172A;--text-muted: #64748B;--error: #EF4444;--nav-bg: #1E293B;--nav-border: #334155;--nav-text: #94A3B8;--nav-hover-bg: #334155}*{box-sizing:border-box;margin:0;padding:0}body{background:var(--bg);color:var(--text);font-family:system-ui,sans-serif;font-size:15px}.app{display:flex;flex-direction:column;min-height:100vh}.navbar{display:flex;align-items:center;gap:2rem;padding:.75rem 2rem;background:var(--nav-bg);border-bottom:1px solid var(--nav-border)}.navbar-brand{display:flex;align-items:center;gap:.75rem;font-size:1.2rem;font-weight:700;color:var(--nav-text);text-decoration:none;transition:color .15s}.navbar-brand:hover{color:#fff;text-decoration:underline}.navbar-logo{width:38px;height:38px;border-radius:50%;object-fit:cover;background:#fff}.navbar-steps{display:flex;gap:.5rem}.navbar-steps a{padding:.4rem .9rem;border-radius:6px;color:var(--nav-text);text-decoration:none;transition:background .15s}.navbar-steps a:hover{background:var(--nav-hover-bg);color:#f1f5f9}.navbar-steps a.active{background:var(--accent);color:#fff}.navbar-disabled{padding:.4rem .9rem;border-radius:6px;color:var(--nav-text);opacity:.4;cursor:default;font-size:.9rem}.stepper{display:flex;align-items:center;gap:0;margin-bottom:2rem;flex-wrap:wrap;gap:.25rem}.stepper-item{display:flex;align-items:center;gap:.25rem}.stepper-flow-label{font-size:.7rem;font-weight:700;color:var(--text-muted);text-transform:uppercase;letter-spacing:.1em;margin-bottom:.5rem}.stepper-arrow{color:var(--text-muted);font-size:1rem;padding:0 .2rem}.stepper-pill{display:flex;align-items:center;gap:.5rem;padding:.4rem .85rem;border-radius:999px;border:2px solid var(--border);background:var(--surface);color:var(--text-muted);font-size:.85rem;font-weight:500;cursor:pointer;transition:border-color .15s,background .15s,color .15s;white-space:nowrap}.stepper-num{display:inline-flex;align-items:center;justify-content:center;width:1.3rem;height:1.3rem;border-radius:50%;background:var(--border);color:var(--text-muted);font-size:.75rem;font-weight:700;flex-shrink:0}.stepper-pill.stepper-active{border-color:var(--accent);background:var(--accent);color:#fff}.stepper-pill.stepper-active .stepper-num{background:#ffffff40;color:#fff}.stepper-pill.stepper-done{border-color:var(--accent);color:var(--accent);background:transparent}.stepper-pill.stepper-done .stepper-num{background:var(--accent);color:#fff}.stepper-pill.stepper-empty{cursor:default}.stepper-pill.stepper-done:hover{border-color:var(--accent-hover);background:#10b98114}.stepper-clear{margin-left:auto;padding:.4rem .9rem;border-radius:999px;border:2px solid #d97706;background:transparent;color:#d97706;font-size:.82rem;font-weight:600;cursor:pointer;transition:background .15s,color .15s;white-space:nowrap}.stepper-clear:hover{background:#d97706;color:#fff}.main-content{flex:1;padding:1.25rem 1.5rem;max-width:1600px;width:100%;margin:0 auto}.page h1{font-size:1.5rem;margin-bottom:1.5rem;color:var(--accent)}.page h2{font-size:1.1rem;margin:1.5rem 0 .75rem}.search-input{width:100%;padding:.6rem 1rem;background:var(--surface);border:1px solid var(--border);border-radius:8px;color:var(--text);font-size:1rem;margin-bottom:1rem;box-sizing:border-box}.search-input:focus{outline:none;border-color:var(--accent)}.search-input-wrap{position:relative;margin-bottom:1rem}.search-input-wrap .search-input{margin-bottom:0;padding-right:2.5rem}.search-input-wrap .spinner{position:absolute;right:.75rem;top:50%;transform:translateY(-50%)}.input-row{display:flex;gap:.5rem;margin-bottom:.75rem}.input-row input{flex:1;padding:.5rem .75rem;background:var(--surface);border:1px solid var(--border);border-radius:6px;color:var(--text)}.trait-table,.pp-table{width:100%;border-collapse:collapse;margin-top:.5rem}.trait-table th,.pp-table th{text-align:left;padding:.5rem .75rem;background:var(--surface);color:var(--text-muted);font-weight:500;border-bottom:1px solid var(--border)}.trait-table td,.pp-table td{padding:.45rem .75rem;border-bottom:1px solid var(--border)}.trait-table tr:hover{background:var(--surface)}.trait-table tr.selected{background:#10b98126}.pmid-link{color:var(--accent);text-decoration:none;font-size:.82rem;white-space:nowrap}.row-checkbox-cell{width:2rem;padding:.45rem .5rem .45rem .75rem!important}.row-checkbox{-moz-appearance:none;appearance:none;-webkit-appearance:none;width:1rem;height:1rem;border:2px solid var(--border);border-radius:3px;background:var(--bg);cursor:pointer;display:block;transition:border-color .15s,background .15s;flex-shrink:0}.row-checkbox:hover{border-color:var(--accent)}.row-checkbox:checked{background:var(--accent);border-color:var(--accent);background-image:url("data:image/svg+xml,%3Csvg viewBox='0 0 10 10' xmlns='http://www.w3.org/2000/svg'%3E%3Cpath d='M1.5 5l2.5 2.5 4.5-4.5' stroke='white' stroke-width='1.5' fill='none' stroke-linecap='round' stroke-linejoin='round'/%3E%3C/svg%3E");background-repeat:no-repeat;background-position:center}.pp-table tr.highlight td{color:#d97706;font-weight:700}.btn-example{margin-bottom:1.5rem;padding:.55rem 1.2rem;background:transparent;color:var(--accent);border:1px solid var(--accent);border-radius:8px;font-size:.9rem;cursor:pointer;transition:background .15s,color .15s}.btn-example:hover{background:var(--accent);color:#fff}.btn-example:disabled{opacity:.4;cursor:not-allowed}.example-bar{display:flex;gap:.75rem;align-items:center;margin-bottom:1.5rem}.example-bar .btn-example{margin-bottom:0}.btn-clear-all{padding:.55rem 1.2rem;background:transparent;color:var(--text-muted);border:1px solid var(--border);border-radius:8px;font-size:.9rem;cursor:pointer;transition:border-color .15s,color .15s}.btn-clear-all:hover{border-color:#ef4444;color:#ef4444}.btn-next,.btn-run{margin-top:1.5rem;padding:.65rem 1.5rem;color:#fff;border:none;border-radius:8px;font-size:1rem;cursor:pointer;transition:background .15s}.btn-next{background:var(--accent)}.btn-next:hover{background:var(--accent-hover)}.btn-run-pending{background:#d97706}.btn-run-pending:hover{background:#b45309}.btn-run-done{background:#94a3b8}.btn-run-done:hover{background:#64748b}.btn-next:disabled,.btn-run:disabled{opacity:.4;cursor:not-allowed}.results-h2{color:var(--accent)}.key-metric{color:#d97706}.page-lead{color:var(--text-muted);margin-bottom:1.25rem;line-height:1.6}.guided-window-row{display:flex;align-items:center;gap:1.5rem;margin-bottom:1.25rem;flex-wrap:wrap}.guided-window-label{display:flex;align-items:center;gap:.5rem;font-size:.9rem;font-weight:500}.guided-window-input{width:80px;padding:.3rem .5rem;border:1px solid var(--border);border-radius:6px;background:var(--surface);color:var(--text);font-size:.9rem;text-align:right}.guided-pop-select{padding:.3rem .5rem;border:1px solid var(--border);border-radius:6px;background:var(--surface);color:var(--text);font-size:.9rem}.guided-window-note{font-size:.82rem;color:var(--text-muted)}.guided-loci-table td.mono{font-family:monospace;font-size:.85rem}.guided-no-t2{background:var(--surface);border:1px solid var(--border);border-radius:8px;padding:1.5rem;color:var(--text-muted);line-height:1.7}.guided-no-t2 a{color:var(--accent)}.guided-controls-row{display:flex;align-items:center;gap:1rem;margin-bottom:1rem;flex-wrap:wrap}.guided-filter-input{flex:1;min-width:220px}.table-scroll{overflow-x:auto}.sortable-th{cursor:pointer;-webkit-user-select:none;user-select:none;white-space:nowrap}.sortable-th:hover{color:var(--accent)}.sort-icon{margin-left:4px;opacity:.4;font-size:.8em}.sort-icon.active{opacity:1;color:var(--accent)}.next-bar-id{font-weight:400;color:var(--text-muted);font-size:.9em;margin-left:4px}.mode-toggle{display:flex;gap:.5rem;margin-bottom:1rem}.mode-toggle button{padding:.4rem 1rem;border:1px solid var(--border);border-radius:6px;background:transparent;color:var(--text-muted);cursor:pointer}.mode-toggle button.active{background:var(--accent);color:#fff;border-color:var(--accent)}.priors-row{display:flex;gap:1.5rem}.priors-row label{display:flex;flex-direction:column;gap:.25rem;color:var(--text-muted);font-size:.9rem}.priors-row input{padding:.4rem .6rem;background:var(--surface);border:1px solid var(--border);border-radius:6px;color:var(--text);width:120px}.ld-pop-row{display:flex;align-items:center;gap:1rem;margin-top:.25rem}.ld-pop-select{padding:.4rem .7rem;background:var(--surface);border:1px solid var(--border);border-radius:6px;color:var(--text);font-size:.9rem;cursor:pointer}.ld-ref-note{font-size:.82rem;color:var(--text-muted)}.ld-ref-note strong{color:var(--text)}.valid{color:var(--accent);margin:.5rem 0}.error{color:var(--error);margin:.5rem 0}.results-box{margin-top:1.5rem;display:flex;flex-direction:column;gap:1.5rem}.pp-section,.venn-section,.top-var-section,.ld-matrix-section,.effect-section,.plot-section{background:var(--surface);border:1px solid var(--border);border-radius:8px;padding:1.25rem 1.5rem;margin-top:0}.results-box .results-h2:first-child{margin-top:0}.pp-headline{display:flex;align-items:baseline;gap:.6rem;margin:.25rem 0 1rem}.pp-headline-value{font-size:2.2rem;font-weight:700;color:#d97706}.pp-headline-label{font-size:.9rem;color:var(--text-muted)}.footer{padding:1rem 2rem;text-align:center;color:var(--text-muted);font-size:.85rem;border-top:1px solid var(--border)}.footer a{color:var(--accent);text-decoration:none}.footer a:hover{text-decoration:underline}.navbar-info{display:flex;gap:.25rem;margin-left:auto}.navbar-info a{padding:.35rem .75rem;border-radius:6px;color:var(--nav-text);text-decoration:none;font-size:.9rem;transition:color .15s}.navbar-info a:hover,.navbar-info a.active{color:var(--accent)}.home-page{max-width:860px;margin:0 auto;width:100%}.home-hero{text-align:center;padding:5rem 1rem 4rem}.home-brand{display:inline-flex;align-items:center;gap:1.5rem;margin-bottom:2rem}.home-logo{width:160px;height:160px;border-radius:50%;object-fit:cover}.home-title{font-size:4.25rem;color:var(--accent);margin:0;font-weight:800;letter-spacing:-.02em}.home-subtitle{font-size:1.2rem;font-weight:500;color:var(--text);margin:0 0 1rem}.home-count{font-size:1rem;color:var(--text-muted);margin-bottom:3rem}.home-count-link{color:inherit;text-decoration:none}.home-count-link:hover strong{text-decoration:underline}.home-count-link strong{font-size:1.1rem;color:var(--accent);font-weight:700}.home-actions{display:flex;justify-content:center;gap:1rem;flex-wrap:wrap}.btn-home-primary{padding:.85rem 2.2rem;background:var(--accent);color:#fff;border:none;border-radius:8px;font-size:1.05rem;font-weight:600;cursor:pointer;transition:background .15s}.btn-home-primary:hover{background:var(--accent-hover)}.btn-home-primary:disabled{opacity:.5;cursor:not-allowed}.btn-home-secondary{padding:.85rem 2.2rem;background:transparent;color:var(--text-muted);border:1.5px solid var(--border);border-radius:8px;font-size:1.05rem;cursor:pointer;transition:border-color .15s,color .15s}.btn-home-secondary:hover{border-color:var(--accent);color:var(--accent)}.about-page,.docs-page{max-width:820px}.about-lead,.docs-lead{font-size:1.05rem;margin-bottom:1.5rem;color:var(--text-muted)}.about-table{border-collapse:collapse;width:100%;margin:.75rem 0 1.25rem;font-size:.9rem}.about-table th,.about-table td{padding:.5rem .9rem;border:1px solid var(--border);text-align:left}.about-table th{background:var(--surface);color:var(--text-muted)}.about-table tr.highlight td{color:var(--accent);font-weight:600}.about-steps,.docs-steps{padding-left:1.5rem;line-height:2.1}.about-refs{padding-left:1.5rem;line-height:1.8;font-size:.9rem;color:var(--text-muted)}.about-page a,.docs-page a{color:var(--accent)}.about-contact{list-style:none;padding:0;line-height:2.2}.copyright-text{font-size:.9rem;color:var(--text-muted)}.cite-box{background:var(--surface);border-left:3px solid var(--accent);padding:1rem 1.25rem;border-radius:0 8px 8px 0;margin:.75rem 0 1.5rem;font-size:.95rem}.disclaimer-box{background:var(--surface);border-left:3px solid #f59e0b;padding:1rem 1.25rem;border-radius:0 8px 8px 0;margin:.75rem 0 1.5rem;font-size:.9rem;line-height:1.7}.docs-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(220px,1fr));gap:1rem;margin:1.5rem 0 2.5rem}.docs-card{display:flex;gap:1rem;align-items:flex-start;padding:1rem 1.2rem;background:var(--surface);border:1px solid var(--border);border-radius:10px;text-decoration:none;color:var(--text);transition:border-color .15s}.docs-card:hover{border-color:var(--accent)}.docs-card-icon{font-size:1.4rem;color:var(--accent);line-height:1}.docs-card strong{display:block;margin-bottom:.2rem}.docs-card p{margin:0;font-size:.82rem;color:var(--text-muted)}.mode-page{max-width:900px}.mode-lead{color:var(--text-muted);margin-bottom:2rem}.mode-grid{display:grid;grid-template-columns:1fr 1fr 1fr;gap:1.25rem}.mode-card{display:flex;gap:1rem;align-items:flex-start;padding:1.4rem 1.5rem;background:var(--surface);border:1px solid var(--border);border-radius:12px;color:var(--text);text-align:left;cursor:pointer;transition:border-color .15s,box-shadow .15s}.mode-card:not(.mode-card-disabled):hover{border-color:var(--accent);box-shadow:0 0 0 3px #10b9811f}.mode-card-disabled{opacity:.45;cursor:default}.mode-card-icon{font-size:1.8rem;color:var(--accent);line-height:1;flex-shrink:0}.mode-card-disabled .mode-card-icon{color:var(--text-muted)}.mode-card-body strong{display:block;font-size:1rem;margin-bottom:.3rem}.mode-card-body p{margin:0;font-size:.83rem;color:var(--text-muted)}.mode-badge{font-size:.68rem;font-weight:600;background:var(--border);color:var(--text-muted);border-radius:4px;padding:1px 5px;margin-left:6px;vertical-align:middle;text-transform:uppercase;letter-spacing:.04em}.docs-page section{margin-top:2.5rem;padding-top:1.5rem;border-top:1px solid var(--border)}.docs-page h3{margin-top:1.25rem;font-size:1rem;color:var(--text-muted);text-transform:uppercase;letter-spacing:.04em}.api-block{display:flex;align-items:center;gap:.75rem;margin:.5rem 0}.api-method{padding:.2rem .55rem;border-radius:4px;font-size:.75rem;font-weight:700;font-family:monospace}.api-method.get{background:#d1fae5;color:#065f46}.api-method.post{background:#dbeafe;color:#1e40af}.api-pre{background:var(--surface);border:1px solid var(--border);border-radius:8px;padding:1rem;font-size:.85rem;margin:.5rem 0 1.25rem;overflow-x:auto}.news-entry{display:flex;gap:1.5rem;margin-bottom:1.5rem}.news-date{font-size:.82rem;color:var(--text-muted);white-space:nowrap;padding-top:.2rem;min-width:90px;font-family:monospace}.news-entry strong{display:block;margin-bottom:.3rem}.news-entry p{margin:0;font-size:.9rem;color:var(--text-muted)}.btn-validate{padding:.5rem 1.1rem;color:#fff;border:none;border-radius:8px;font-size:.9rem;cursor:pointer;white-space:nowrap;transition:background .15s}.btn-validate-pending{background:#d97706}.btn-validate-pending:hover{background:#b45309}.btn-validate-done{background:#94a3b8}.btn-validate-done:hover{background:#64748b}.try-chips{display:flex;flex-wrap:wrap;align-items:center;gap:.4rem;margin-bottom:1rem}.try-label{font-size:.82rem;color:var(--text-muted);margin-right:.2rem}.try-chip{padding:.25rem .7rem;border:1px solid var(--border);border-radius:999px;background:var(--surface);color:var(--text-muted);font-size:.82rem;cursor:pointer;transition:border-color .15s,color .15s;white-space:nowrap}.try-chip:hover{border-color:var(--accent);color:var(--accent)}.try-chip-sub{font-size:.72rem;opacity:.7;margin-left:.3rem}.selection-row{display:flex;align-items:center;gap:.5rem;margin-bottom:1.25rem;font-size:.9rem}.selection-check{color:var(--accent)}.selection-name{font-weight:600;color:var(--text)}.selection-id{font-family:monospace;font-size:.82rem;color:var(--text-muted)}.btn-clear-trait{background:transparent;border:none;color:var(--text-muted);cursor:pointer;font-size:.75em;padding:0 .3rem;vertical-align:middle;line-height:1}.btn-clear-trait:hover{color:var(--error)}.result-count{color:var(--text-muted);font-size:.85rem;margin-bottom:.5rem}.loading{color:var(--text-muted)}.traits-summary{display:flex;gap:1rem;margin-bottom:1.5rem}.trait-chip{flex:1;padding:.6rem 1rem;background:var(--surface);border:1px solid var(--border);border-radius:8px;font-size:.9rem}.chip-label{display:block;color:var(--accent);font-size:.75rem;font-weight:600;text-transform:uppercase;margin-bottom:.2rem}.analysis-summary{background:var(--surface);border:1px solid var(--border);border-radius:8px;padding:1rem 1.25rem;margin-bottom:1.5rem}.summary-row{display:flex;gap:1rem;padding:.35rem 0;border-bottom:1px solid var(--border)}.summary-row:last-child{border-bottom:none}.summary-label{min-width:80px;color:var(--accent);font-weight:600;font-size:.85rem}.missing{color:var(--error);font-style:italic}.original-id{color:var(--text-muted);font-size:.82rem}.pmid-link{color:var(--accent);text-decoration:none;font-size:.85rem}.pmid-link:hover{text-decoration:underline}.pmid-icon{color:var(--text-muted);text-decoration:none;font-size:.8rem;padding:0 .2rem}.pmid-icon:hover{color:var(--accent)}.results-meta{margin-top:1rem;font-size:.9rem;color:var(--text-muted)}.results-meta strong{color:var(--text)}.results-meta p{margin:.3rem 0}.top-var-table{width:100%;border-collapse:collapse;margin-top:.75rem;font-size:.88rem}.top-var-table th{background:var(--surface);color:var(--text-muted);font-weight:500;padding:.45rem .75rem;border-bottom:1px solid var(--border);text-align:left}.top-var-table td{padding:.5rem .75rem;border-bottom:1px solid var(--border);vertical-align:top}.top-var-label{font-size:.82rem;color:var(--text-muted);white-space:nowrap;font-weight:500}.top-var-desc{font-size:.82rem;color:var(--text-muted);font-style:italic}.top-var-trait{display:block;font-size:.78rem;font-style:italic;margin-top:.15rem}.venn-section{margin-top:1.5rem}.venn-subtitle{font-size:.85rem;color:var(--text-muted);margin:.2rem 0 .6rem}.venn-subtitle strong{color:var(--text)}.venn-v-wrap{display:flex;flex-direction:column;align-items:center}.venn-v-svg{width:100%;max-width:480px}.venn-v-c1,.venn-v-c2{fill:#10b9812e;stroke:#10b981;stroke-width:2.5}.venn-v-title-t1,.venn-v-title-t2{font-size:12px;font-weight:700;fill:#10b981;font-family:inherit}.venn-v-num{font-size:20px;font-weight:700;fill:#0f172a;font-family:inherit}.venn-v-sub{font-size:10.5px;fill:#334155;font-family:inherit}.top-var-section{margin-top:1.5rem}.results-count-row{display:flex;align-items:center;gap:.75rem;margin:.4rem 0 .6rem}.results-count{font-size:.82rem;color:var(--text-muted)}.page-size-row{display:flex;align-items:center;gap:.4rem;font-size:.82rem;color:var(--text-muted);margin-left:0}.segmented-control{display:inline-flex;border:1px solid var(--border);border-radius:6px;overflow:hidden}.segmented-btn{padding:.2rem .65rem;border:none;border-right:1px solid var(--border);background:transparent;color:var(--text-muted);font-size:.82rem;cursor:pointer;transition:background .15s}.segmented-btn:last-child{border-right:none}.segmented-btn.active{background:var(--primary);color:#fff}.pagination-row{display:flex;align-items:center;justify-content:center;gap:.75rem;margin-top:.75rem;padding:.5rem 0;border-top:1px solid var(--border)}.pagination-btn{padding:.25rem .7rem;border:1px solid var(--border);border-radius:4px;background:transparent;color:var(--text);font-size:1rem;cursor:pointer}.pagination-btn:disabled{opacity:.3;cursor:default}.pagination-info{font-size:.85rem;color:var(--text-muted)}.ld-matrix-section{margin-top:1.5rem}.ld-matrix-note{font-size:.82rem;color:var(--text-muted);margin:.25rem 0 .75rem}.ld-matrix-note strong{color:var(--text)}.ld-matrix-wrap{overflow-x:auto}.ld-matrix-table{border-collapse:collapse;font-size:.82rem}.ld-matrix-corner{min-width:140px}.ld-matrix-col-header{padding:.4rem .6rem;text-align:center;border:1px solid var(--border);background:var(--surface);max-width:180px}.ld-matrix-row-header{padding:.4rem .75rem;border:1px solid var(--border);background:var(--surface);white-space:nowrap}.ld-matrix-role{display:block;font-size:.82rem;font-weight:600;color:var(--text)}.ld-matrix-varid{display:block;font-family:monospace;font-size:.72rem;color:var(--text-muted);margin-top:.15rem}.ld-matrix-cell{width:68px;height:44px;text-align:center;font-weight:600;border:1px solid rgba(255,255,255,.08);font-size:.85rem}@keyframes spin{to{transform:rotate(360deg)}}@keyframes spinner-appear{to{opacity:1}}.spinner{width:1.4rem;height:1.4rem;border:2px solid var(--border);border-top-color:var(--accent);border-radius:50%;animation:spin .7s linear infinite;display:inline-block;vertical-align:middle}.spinner-delayed{opacity:0;animation:spin .7s linear infinite,spinner-appear 0s .2s forwards}.loading-row{display:flex;align-items:center;gap:.75rem;margin-top:1rem;color:var(--text-muted);font-size:.9rem}.img-wrapper{position:relative}.img-spinner{position:absolute;top:0;right:0;bottom:0;left:0;display:flex;align-items:center;justify-content:center;background:#ffffffd9}.btn-secondary{margin-top:1.25rem;padding:.55rem 1.25rem;background:transparent;border:1px solid var(--border);border-radius:8px;color:var(--text-muted);cursor:pointer}.btn-secondary:hover{border-color:var(--accent);color:var(--accent)}.locuszoom-grid{display:grid;grid-template-columns:1fr 1fr;gap:1rem}@media (max-width: 700px){.locuszoom-grid{grid-template-columns:1fr}}.locuszoom-wrap{border:1px solid var(--border);border-radius:8px;overflow:hidden}.locuszoom-label{font-size:.82rem;font-weight:600;color:var(--text-muted);text-transform:uppercase;letter-spacing:.05em;margin:1.25rem 0 .5rem}.venn-counts{display:flex;align-items:center;justify-content:center;gap:0;margin:1rem 0}.venn-count-item{display:flex;flex-direction:column;align-items:center;background:var(--surface);border:1px solid var(--border);border-radius:8px;padding:.6rem 1.25rem;min-width:120px}.venn-count-item strong{font-size:1.4rem;color:var(--accent)}.venn-count-item span{font-size:.78rem;color:var(--text-muted);text-align:center;margin-top:.15rem;max-width:140px}.venn-count-intersect{display:flex;flex-direction:column;align-items:center;background:#fff;border-top:1px solid var(--border);border-bottom:1px solid var(--border);padding:.6rem 1.25rem;min-width:140px;position:relative}.venn-count-intersect:before,.venn-count-intersect:after{content:"∩";position:absolute;top:50%;transform:translateY(-50%);color:var(--border);font-size:1.2rem}.venn-count-intersect:before{left:-.8rem}.venn-count-intersect:after{right:-.8rem}.venn-count-intersect strong{font-size:1.4rem;color:var(--text)}.venn-count-intersect span{font-size:.78rem;color:var(--text-muted);text-align:center;margin-top:.15rem}.venn-wrapper{margin-top:1.5rem;display:flex;flex-direction:column;align-items:center;gap:.75rem}.venn-svg{width:100%;max-width:360px}.venn-circle{fill:transparent;stroke-width:2}.venn-c1,.venn-c2{stroke:var(--accent);fill:#10b98112}.venn-label{fill:var(--text);font-size:11px;font-family:inherit}.venn-label-sm{fill:var(--text-muted);font-size:10px;font-family:inherit;font-style:italic}.venn-empty{fill:var(--text-muted);font-size:22px;font-family:inherit}.venn-message{color:var(--text-muted);font-size:.9rem;text-align:center}.effect-section{margin-top:1.5rem}.effect-table{border-collapse:collapse;margin-top:.75rem}.effect-table th,.effect-table td{padding:.5rem 1.2rem;border:1px solid var(--border);text-align:center}.effect-table th{background:var(--surface);font-size:.85rem;color:var(--text-muted)}.variant-id{font-family:monospace;font-size:.85rem;text-align:left;color:var(--text-muted)}.effect-allele{font-family:monospace;font-size:.95rem;font-weight:600;color:var(--text);text-align:center}.effect-pos{font-size:1.4rem;font-weight:700;color:#10b981}.effect-neg{font-size:1.4rem;font-weight:700;color:#ef4444}.effect-na{font-size:1.2rem;color:var(--text-muted)}.plot-section{margin-top:1.5rem}.coloc-plot{max-width:100%;border-radius:8px;border:1px solid var(--border);background:#fff}.download-section{margin-top:1.5rem}.download-buttons{display:flex;flex-wrap:wrap;gap:.75rem;margin-top:.75rem}.btn-download{padding:.55rem 1.1rem;background:var(--surface);border:1px solid var(--border);border-radius:8px;color:var(--text);cursor:pointer;font-size:.9rem;transition:border-color .15s}.btn-download:hover{border-color:var(--accent);color:var(--accent)}.btn-download-primary{background:var(--accent);border-color:var(--accent);color:#fff}.btn-download-primary:hover{background:var(--accent-hover);color:#fff}.table-header{display:flex;justify-content:space-between;align-items:center;margin-bottom:.5rem}.table-footer{display:flex;justify-content:flex-end;margin-top:.75rem}.fetching{color:var(--text-muted);font-size:.85rem}.pagination{display:flex;align-items:center;gap:.25rem}.page-btn{min-width:2rem;padding:.3rem .5rem;background:var(--surface);border:1px solid var(--border);border-radius:5px;color:var(--text-muted);cursor:pointer;font-size:.85rem}.page-btn:hover:not(:disabled){border-color:var(--accent);color:var(--text)}.page-btn.active{background:var(--accent);border-color:var(--accent);color:#fff}.page-btn:disabled{opacity:.35;cursor:not-allowed}.page-ellipsis{color:var(--text-muted);padding:0 .25rem}.mode-section-title{font-size:1rem;font-weight:600;color:var(--text-muted);text-transform:uppercase;letter-spacing:.05em;margin:2rem 0 .5rem}.mode-section-desc{font-size:.88rem;color:var(--text-muted);margin:0 0 1rem}.mode-card-upload{border-style:dashed}.mode-card-upload:hover{border-style:solid}.upload-dropzone{display:flex;flex-direction:column;align-items:center;justify-content:center;gap:.5rem;padding:2.5rem 2rem;border:2px dashed var(--border);border-radius:12px;background:var(--surface);cursor:pointer;transition:border-color .15s,background .15s;min-height:130px;text-align:center;margin-bottom:1.25rem}.upload-dropzone:hover,.upload-dropzone.dragging{border-color:var(--accent);background:#10b9810a}.upload-dropzone.has-result{border-style:solid;border-color:var(--accent)}.upload-icon{font-size:2rem;color:var(--accent)}.upload-hint{font-size:.95rem;color:var(--text)}.upload-sub{font-size:.78rem;color:var(--text-muted)}.upload-error{background:#ef444414;border:1px solid rgba(239,68,68,.3);border-radius:8px;padding:1rem 1.25rem;margin-bottom:1rem}.upload-error strong{display:block;color:#ef4444;margin-bottom:.4rem}.upload-error pre{margin:0;font-size:.82rem;white-space:pre-wrap;color:var(--text)}.upload-result{background:var(--surface);border:1px solid var(--border);border-radius:8px;padding:.85rem 1.25rem;margin-bottom:1rem;display:flex;flex-direction:column;gap:.4rem}.upload-result-row{display:flex;gap:1rem;align-items:baseline;font-size:.9rem}.upload-result-label{color:var(--text-muted);min-width:130px;flex-shrink:0}.upload-warnings{margin-top:.5rem;font-size:.82rem;color:#f59e0b;display:flex;flex-direction:column;gap:.2rem}.upload-field{display:flex;flex-direction:column;gap:.4rem;margin-bottom:1rem}.upload-field label{font-size:.9rem;font-weight:500}.upload-field input{padding:.55rem .85rem;border:1px solid var(--border);border-radius:8px;background:var(--surface);color:var(--text);font-size:.95rem}.upload-field input:focus{outline:none;border-color:var(--accent)}.upload-field-hint{font-weight:400;color:var(--text-muted);font-size:.82rem}.required{color:#ef4444}.upload-badge{font-size:.8rem;color:var(--accent);background:color-mix(in srgb,var(--accent) 12%,transparent);border-radius:4px;padding:1px 6px;margin-left:4px}.btn-clear-upload{display:inline-block;margin-top:.25rem;padding:.3rem .85rem;font-size:.82rem;border:1px solid var(--border);border-radius:6px;background:transparent;color:var(--text-muted);cursor:pointer}.btn-clear-upload:hover{border-color:#ef4444;color:#ef4444}.upload-examples-hint{margin:0 0 1rem;font-size:.85rem;color:var(--text-muted)}.source-toggle{display:flex;border:1px solid var(--border);border-radius:8px;overflow:hidden;width:fit-content;margin-bottom:1.5rem}.source-toggle-btn{padding:.45rem 1.2rem;font-size:.9rem;border:none;background:transparent;cursor:pointer;color:var(--text-muted);transition:background .15s,color .15s}.source-toggle-btn.active{background:var(--accent);color:#fff}.source-toggle-btn:hover:not(.active){background:var(--surface);color:var(--text)}.examples-panel{margin-bottom:1.25rem}.examples-toggle{cursor:pointer;font-size:.85rem;color:var(--accent);-webkit-user-select:none;user-select:none;list-style:none}.examples-toggle:hover{text-decoration:underline}.examples-toggle::-webkit-details-marker{display:none}.examples-body{margin-top:.6rem;padding:.85rem 1rem;background:var(--surface);border:1px solid var(--border);border-radius:8px}.examples-desc{font-size:.83rem;color:var(--text-muted);margin:0 0 .6rem}.examples-table{width:100%;border-collapse:collapse}.examples-table td{padding:.45rem .5rem;border-top:1px solid var(--border);font-size:.85rem;vertical-align:middle}.examples-table tr:first-child td{border-top:none}.examples-sub{font-size:.76rem;color:var(--text-muted);display:block;margin-top:.1rem}.examples-dl-cell{text-align:right;white-space:nowrap}.btn-download-example{display:inline-block;padding:.2rem .7rem;border:1px solid var(--accent);color:var(--accent);border-radius:4px;text-decoration:none;font-size:.8rem;background:transparent}.btn-download-example:hover{background:var(--accent);color:#fff}.session-bar{display:flex;flex-wrap:wrap;gap:.5rem 1.5rem;padding:.45rem 1.5rem;background:var(--surface);border-bottom:1px solid var(--border);font-size:.82rem;color:var(--text-muted)}.session-item{display:flex;align-items:center;gap:.35rem}.session-label{font-weight:600;color:var(--accent);text-transform:uppercase;font-size:.72rem;letter-spacing:.04em}.session-item .upload-badge{font-size:.72rem}.session-flow{font-weight:600;color:var(--text);border-right:1px solid var(--border);padding-right:1.5rem}